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PF-05175157
Item number: TGM-T7163-100mg
Description: PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively. Target: Acetyl-CoA Carboxylase. Smiles: CC(C)n1ncc2CC3(CCN(CC3)C(=O)c3ccc4nc(C)[nH]c4c3)CC(=O)c12. References: Jiménez de Oya,...
| Application: | ACC inhibitor |
| CAS | 1301214-47-0 |
| MW: | 405.49 D |
From 60.00€
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PF-05175157
Item number: Cay21778-1
PF-05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2, respectively). It inhibits formation of malonyl-CoA in primary rat hepatocytes (EC50 = 29.9 nM). In vivo, PF-05175157 inhibits formation of malonyl-CoA in the...
| Keywords: | 1,4-dihydro-1'-[(2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4'-piperidin]-7(6H)-one |
| Application: | ACC inhibitor |
| CAS | 1301214-47-0 |
| MW: | 405.5 D |
From 45.00€
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