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Item number: Cay24098-1

Ganirelix is a gonadotropin-releasing hormone receptor (GNRHR) antagonist (IC50 = 3.6 nM, pA2 = 9.3). It induces a concentration-dependent increase in histamine release from rat peritoneal mast cells in vitro (EC50 = 11 µg/ml). In vivo, ganirelix (2 mg/kg, s.c.) decreases plasma testosterone in intact male rats for...

Keywords:	N-acetyl-3-(2-naphthalenyl)-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-seryl-L-tyrosyl-N6-[(ethylamino)(e...
Application:	Gonadotropin-releasing hormone receptor antagonist
CAS	129311-55-3
MW:	1690.4 D

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