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Item number: Cay23974-25

PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 µM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 µM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and lambda-carrageenan ex vivo...

Keywords:	4-[[(2S)-2-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]amino]-1-oxo-3-phenylpropyl]amino]-benzeneacetic acid,...
Application:	Plasma kallikrein inhibitor
CAS	128837-71-8
MW:	474 D

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