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GSK2578215A
GSK2578215A

Item number: Cay14603-5

GSK2578215A is a potent inhibitor of leucine-rich repeat kinase 2 (LRRK2, IC50 = 8.9 nM) that also inhibits the G2019S mutant of LRRK2 (IC50 = 10.1 nM). It displays selectivity for LRRK2 over a panel of 460 other kinases. GSK2578215A prevents phosphorylation of both wild-type and G2019S LRRK2 in mouse spleen and...
Keywords: 5-(2-fluoro-4-pyridinyl)-2-(phenylmethoxy)-N-3-pyridinyl-benzamide
Application: LRRK2 inhibitor
CAS 1285515-21-0
MW: 399.4 D
From 78.00€ *
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GSK-2578215A
GSK-2578215A

Item number: LKT-G733400.100

Keywords: GSK2578215A, Q641JSF42X, CHEMBL2204495,GSK257821A, AK174163,...
Application: LRRK2 inhibitor
CAS 1285515-21-0
MW: 399.43 D
From 123.00€ *
Review
GSK2578215A
GSK2578215A

Item number: TGM-T2240-100mg

Description: GSK2578215A is a potent and selective LRRK2 kinase inhibitor. Target: Autophagy, Mitophagy, LRRK2. Smiles: Fc1cc(ccn1)-c1ccc(OCc2ccccc2)c(c1)C(=O)Nc1cccnc1. References: Reith AD, et al. Bioorg Med Chem Lett. 2012, 22(17), 5625-5629.
Application: LRRK2 inhibitor
CAS 1285515-21-0
MW: 399.42 D
From 30.00€ *
Review