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Item number: TGM-T84493-10mg

Description: 1CAY10649, a thiazolinone compound, directly inhibits 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) with an IC50 value of 0.28 µM and in a soluble fraction of an S100 PMNL cell lysate with an IC50 value of 0.09 µM, following stimulation by calcium and arachidonic...

CAS	1272519-89-7
MW:	329.8 D

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CAY10649

Item number: Cay10804-1

5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction. CAY10649 is a thiazolinone compound that demonstrates direct inhibition of 5-lipoxygenase (5-LO) product...

Keywords:	(Z)-2-(4-chlorophenyl)-5-(4-methoxybenzylidene)thiazol-4(5H)-one
Application:	5-LO inhibitor
CAS	1272519-89-7
MW:	329.8 D

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