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Item number: Cay15129-1

Microsomal prostaglandin E synthase-1 (mPGES-1) converts the COX product PGH2 into the biologically active PGE2. Like COX-2, the expression of mPGES-1 is induced in response to pro-inflammatory mediators, including LPS, IL-1beta, and TNF-alpha. CAY10678 is a benzoimidazole that potently inhibits human and rat...

Keywords:	mPGES-1 Inhibitor III, N-cyclopentyl-1-[5,6-dimethyl-1-(1-methylethyl)-1H-benzimidazol-2-yl]-4-piperidinecarboxamide
Application:	mPGES-1 inhibitor
CAS	1268709-57-4
MW:	382.5 D

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