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(+)-JQ1
Item number: Cay11187-5
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces...
| Keywords: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid,... |
| Application: | BRD4 inhibitor |
| CAS | 1268524-70-4 |
| MW: | 457 D |
From 35.00€
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(+)-JQ-1
Item number: TGM-T2110-100mg
Description: (+)-JQ-1 (JQ1) is a specific, reversible BET bromine domain inhibitor that targets BRD4 (1/2) with IC50 values of 77/33 nM. (+)-JQ-1 induces cell autophagy and inhibits cell proliferation. Target: Autophagy, Epigenetic Reader Domain, Ligands for Target Protein for PROTAC. Smiles:...
| Keywords: | JQ1 |
| Application: | BRD4 inhibitor |
| CAS | 1268524-70-4 |
| MW: | 456.99 D |
From 31.00€
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(+)-JQ-1
Item number: LKT-J6400.1
JQ-1 is a triazolothienodiazepine compound that inhibits the BET bromodomain (BRD) family of proteins. Although it is a diazepine-like compound, JQ-1 exhibits no sedative or anxiolytic efficacy. JQ-1 was initially in development as a non-hormonal male contraceptive, inhibiting bromodomain testis-specific protein...
| Application: | Bromodomain Inhibitor |
| CAS | 1268524-70-4 |
| MW: | 456.99 D |
From 112.00€
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(+)-JQ1
Item number: SYN-3004-M001
Soluble in DMSO or ethanol. (+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor (IC(50) values of 17.7, 32.6, 76.9 and 12942nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP, respectively. Target: BET bromodomain
| Application: | BET bromodomain inhibitor |
| CAS | 1268524-70-4 |
| MW: | 457 D |
From 165.00€
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