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Nilotinib-d6
Item number: TGM-T12224-10mg
Description: Nilotinib D6 is a deuterium labeled Nilotinib which is an orally available inhibitor of Bcr-Abl tyrosine kinase ,and with antineoplastic activity. Smiles: [2H]c1c([2H])c(c(Nc2nccc(n2)-c2cccnc2)c([2H])c1C(=O)Nc1cc(cc(c1)C(F)(F)F)-n1cnc(C)c1)C([2H])([2H])[2H]. References: Weisberg E, et al. Beneficial...
| Keywords: | AMN107 D6 |
| Application: | Internal standard, GC, LC-MS |
| CAS | 1268356-17-7 |
| MW: | 535.55 D |
From 276.00€
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Nilotinib-d6
Item number: Cay19280-1
Nilotinib-d6 is intended for use as an internal standard for the quantification of nilotinib (Cay-10010422, Cay-36628) by GC- or LC-MS. Nilotinib is an inhibitor of wild-type and mutant Bcr-Abl (IC50s = 15 and 9-400 nM, respectively). It is selective for wild-type and mutant Bcr-Abl over Src and LYN (IC50s = >5,000...
| Keywords: | 4-(methyl-d3)-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-5-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-benzami... |
| Application: | Internal standard, GC, LC-MS |
| CAS | 1268356-17-7 |
| MW: | 535.6 D |
707.00€
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