2 products were found matching "1262238-11-8"!
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INCB3344
Item number: TGM-TQ0103-100mg
Description: INCB3344 is an effective, specific and orally bioavailable CCR2 antagonist with IC50 values of 9.5 nM (mCCR2) and 5.1 nM (hCCR2) in binding antagonism and 7.8 nM (mCCR2) and in 3.8 nM (hCCR2) antagonism of chemotaxis activity. Target: CCR. Smiles:...
| Application: | CCR2 antagonist |
| CAS | 1262238-11-8 |
| MW: | 577.59 D |
From 63.00€
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INCB 3344
Item number: Cay28433-1
INCB 3344 is an antagonist of chemokine (C-C motif) receptor 2 (CCR2, IC50 = 10 nM in WEHI-274 murine monocytes). It is selective for CCR2 over a panel of G protein-coupled receptors, including CCR1 and CCR5, with IC50s values greater than 1 µM. INCB 3344 inhibits chemotaxis of WEHI-274 cells induced by chemokine...
| Keywords: | rel-N-[2-[[(3R,4R)-1-[trans-4-(1,3-benzodioxol-5-yl)-4-hydroxycyclohexyl]-4-ethoxy-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(tr... |
| Application: | CCR2 antagonist |
| CAS | 1262238-11-8 |
| MW: | 577.6 D |
From 125.00€
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