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Item number: Cay30063-5

TCS 21311 is an inhibitor of JAK3 (IC50 = 8 nM in an enzyme assay). It is selective for JAK3 over JAK1, JAK2, and tyrosine kinase 2 (TYK2, IC50s = 1,017, 2,550, and 8,055 nM, respectively) but does inhibit glycogen synthase kinase 3beta (GSK-3beta), PKCalpha, and PKCtheta (IC50s = 13, 68, and 3 nM, respectively)....

Keywords:	NIBR3049,...
Application:	JAK3 inhibitor
CAS	1260181-14-3
MW:	526.5 D

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