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Item number: TGM-T10350-1mg

Description: Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM). Apremilast inhibits TNF-alpha release by lipopolysaccharide (IC50: 104 nM). Smiles:...

Keywords:	Apremilast D5, CC-10004 D5
CAS	1258597-47-5
MW:	465.53 D

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Apremilast-d5

Item number: Cay22553-1

Apremilast-d5 is intended for use as an internal standard for the quantification of apremilast (Cay-18502) by GC- or LC-MS. Apremilast is an inhibitor of phosphodiesterase 4 (PDE4) with an IC50 value of 74 nM when tested in U937 cell lysates with 1 mM cAMP. It is orally active, significantly decreasing epidermal...

Keywords:	N-[2-[(1S)-1-[3-(ethoxy-1,1,2,2,2-d5)-4-methoxyphenyl]-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-ac...
Application:	GC-MS, LC-MS, internal standard, PDE4 inhibitor
CAS	1258597-47-5
MW:	465.5 D

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