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PTC299
Item number: TGM-T12574-100mg
Description: PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA translation and selectively inhibits VEGF protein synthesis at the post-transcriptional level. PTC299 is also a potent inhibitor of dihydrolactate...
| Keywords: | Emvododstat, (4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate |
| Application: | Targets vascular endothelial growth factor A (VEGFA) |
| CAS | 1256565-36-2 |
| MW: | 467.34 D |
From 119.00€
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Emvododstat
Item number: Cay36877-1
Emvododstat is an inhibitor of dihydroorotate dehydrogenase (DHODH). It inhibits DHODH by 89% in HeLa cells when used at a concentration of 100 nM. Emvododstat inhibits hypoxia-induced VEGF-A synthesis in HeLa cells (EC50 = 1.64 nM). It inhibits viral replication of severe acute respiratory syndrome coronavirus 2...
| Keywords: | PTC-299, (1S)-6-chloro-1,3,4,9-tetrahydro-1-(4-methoxyphenyl)-2H-pyrido[3,4-b]indole-2-carboxylic acid, 4-chlorophenyl ester |
| Application: | DHODH inhibitor |
| CAS | 1256565-36-2 |
| MW: | 467.3 D |
From 107.00€
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