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Item number: TGM-T83909-50mg

Description: 6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4. This compound exhibits affinity for the serotonin (5-HT) receptor subtype 5-HT1A, demonstrating efficacy in the rat hippocampus and dorsal raphe with half-maximal...

Keywords:	BMY 28674, BMS-52821
Application:	Active buspirone metabolite
CAS	125481-61-0
MW:	401.5 D

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6-hydroxy Buspirone

Item number: Cay39807-1

6-hydroxy Buspirone is an active metabolite of the anxiolytic buspirone. It is formed from buspirone by the cytochrome P450 (CYP) isoform CYP3A4. 6-hydroxy Buspirone binds to the serotonin (5-HT) receptor subtype 5-HT1A in rat hippocampus and dorsal raphe (EC50s = 4 and 1 µM, respectively) and is a dopamine D2, D3,...

Keywords:	BMS-52821, BMY 28674, 6-hydroxy-8-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione
Application:	Active buspirone metabolite
CAS	125481-61-0
MW:	401.5 D

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