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Item number: TGM-T7494-100mg

Description: TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 µM). Target: GluR. Smiles: Nc1nccc(\C=C\c2ccccc2)n1. References: Pershina E V , Arkhipov V I . Subacute activation of mGlu4 receptors causes the feedback inhibition of its...

Keywords:	TCN 238
Application:	Positive allosteric mGluR4 modulator
CAS	125404-04-8
MW:	197.24 D

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TCN 238

Item number: Cay11994-10

TCN 238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4, EC50 = 1 µM). It has a greater than 30-fold selectivity for mGluR4 over mGluR5 using human recombinant receptors in CHO-K1 cells. It has no activity at the adenosine A2A, serotonin 5-HT1A, or...

Keywords:	(E)-4-(2-phenylethenyl)-2-pyrimidinamine
Application:	Positive allosteric mGluR4 modulator
CAS	125404-04-8
MW:	197.2 D

From 133.00€ *

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