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CD437
CD437

Item number: TGM-T4371-100mg

Description: CD437 (AHPN) is a specifc Retinoic Acid Receptor gamma (RARgamma) agonist. Target: Autophagy, Retinoid Receptor. Smiles: OC(=O)c1ccc2cc(ccc2c1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2. References: Li Y, et al. Molecular determinants of AHPN (CD437)-induced growth arrest and apoptosis in human lung cancer...
Keywords: AHPN, Apoptosis Activator VI, O-Desmethyl Adapalene
Application: RAR gamma agonist
CAS 125316-60-1
MW: 398.49 D
From 34.00€ *
Review
CD437
CD437

Item number: Cay71610-5

CD437 is the prototypical adamantyl arotinoid of the retinoid-related molecule family that acts as a selective agonist of retinoic acid receptor (RAR)gamma (Kds = 6.5 µM, 2.5 µM, and 77 nM for RARalpha, beta, and gamma, respectively). CD437 is cytotoxic to the acute myeloid leukemia cell line NB4 (EC50 = 0.17 µM),...
Keywords: AHPN, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid
Application: RAR gamma agonist
CAS 125316-60-1
MW: 398.5 D
From 115.00€ *
Review