Description: Pleuromutilin (Drosophilin B) is an inhibitor of bacterial protein synthesis by binding to the 50S ribosomal subunit of bacteria. Target: Antibiotic, Antibacterial. Smiles: C[C@@H]1[C@]23[C@]([C@](C)([C@H](OC(CO)=O)C[C@](C=C)(C)[C@H]1O)[C@H](C)CC2)(C(=O)CC3)[H]. References: Shang RF et al. Synthesis...

Pleuromutilin is an antibiotic derived from the fungus Clitopilus that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase component of the 50S subunit and inhibiting peptide bond formation.Formal Name: 2-hydroxy-acetic acid,...

Pleuromutilin is a diterpene produced by several species of basidomycetes, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria with no cross resistance to existing antibiotic classes due to its unique mode of...