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Losartan Carboxylic Acid
Item number: TGM-T3461-100mg
Description: Losartan Carboxylic Acid (E-3174), a potent AT1 antagonist (Kis: 0.57 nM, rat, 0.67 nM, human), produces a depressor response and vasodilatation. As a metabolite of losartan, it is more potent than losartan in blocking angiotensin II-induced responses in vascular smooth muscle cells. Target: RAAS....
| Keywords: | EXP-3174, E-3174 |
| Application: | AGTR1 antagonist |
| CAS | 124750-92-1 |
| MW: | 436.89 D |
From 43.00€
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Losartan Carboxylic Acid
Item number: Cay15957-5
Losartan carboxylic acid is an antagonist of the angiotensin II type 1b (AT1b) receptor (Ki = 0.67 nM in COS-7 cells expressing the human receptor) and an active metabolite of losartan (Cay-10006594). It is formed from losartan by the cytochrome P450 (CYP) isoform CYP2C9. Losartan carboxylic acid is selective for...
| Keywords: | E-3174, EXP-3174, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylic acid |
| Application: | AGTR1 antagonist |
| CAS | 124750-92-1 |
| MW: | 436.9 D |
From 50.00€
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![EXP 3174 (Losartan Carboxylic acid) (2-Butyl-4-chloro-1-[[2Õ-(1H-tetrazol-5-yl)[1,1Õ-biphenyl]-4-yl]](https://www.biomol.com/media/image/c7/de/d3/E9009-10_200x200.jpg "EXP 3174 (Losartan Carboxylic acid) (2-Butyl-4-chloro-1-[[2Õ-(1H-tetrazol-5-yl)[1,1Õ-biphenyl]-4-yl]")
EXP 3174 (Losartan Carboxylic acid)...
Item number: E9009.10
A metabolite of Losartan. Melting Point: As Reported, Solubility: As Reported, Method for Determining Identity: Proton NMR (DMSO-d6) Spectroscopic and Mass Spectroscopic Analysis, TLC Conditions: As Reported, Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at...
| CAS | 124750-92-1 |
| MW: | 436.89 D |
From 493.00€
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