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TK05
TK05

Item number: TGM-T13165-100mg

Description: TK05 is a potent and selective leukotriene C4 synthase (LTC4S) inhibitor with an IC50 of 95 nM. Target: Others. Smiles: COc1ccc(cc1)C(=O)c1ccc(cc1C(O)=O)C(=O)c1ccc(cn1)N(CC1CC1)c1ccc(Cl)cc1. References: Kleinschmidt TK, et al. Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human...
CAS 1245734-61-5
MW: 540.99 D
From 1,520.00€ *
Review
TK05
TK05

Item number: Cay19793-1

TK05 is an inhibitor of leukotriene C4 (LTC4) synthase (IC50 = 95 nM). It is selective for LTC4 synthase over microsomal prostaglandin E synthase-1 (mPGES-1), microsomal glutathione S-transferase 2 (GST2), and 5-lipoxygenase (5-LO) at 10 µM. TK05 (1 µM) inhibits LTC4 synthase in Mono-Mac-6 leukemia cells and...
Keywords: 5-[[5-[(4-chlorophenyl)(cyclopropylmethyl)amino]-2-pyridinyl]carbonyl]-2-(4-methoxybenzoyl)-benzoic acid
Application: LTC4 synthase inhibitor
CAS 1245734-61-5
MW: 541 D
From 153.00€ *
Review