- Search results for 1245537-68-1
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4 products were found matching "1245537-68-1"!
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Item number: TGM-T6072-100mg
Description: BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kalpha/beta/gamma (IC50: 4/63/38 nM) . Target: Autophagy, PI3K, mTOR, Apoptosis. Smiles: OC(=O)\C=C/C(O)=O.COc1ccc(cn1)-c1ccc2ncc3n(C)c(=O)n(-c4ccc(N5CCNCC5)c(c4)C(F)(F)F)c3c2c1. References: Markman B, et al. Ann Oncol, 2012, 23(9),...
Keywords: | NVP-BGT226, NVP-BGT226 (maleate), BGT226 |
Application: | Dual PI3K / FRAP inhibitor |
CAS | 1245537-68-1 |
MW: | 650.6 D |
From 53.00€
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Item number: LKT-N8604.1
NVP-BGT225 is an inhibitor of PI3K and mTORC1/2.
Keywords: | BGT226 |
Application: | PI3K / mTOR inhibitor |
CAS | 1245537-68-1 |
MW: | 650.6 D |
From 205.00€
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Item number: Cay22142-1
NVP-BGT226 is an orally bioavailable dual inhibitor of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR). It inhibits class I PI3Ks with EC50 values of 4, 63, and 38 nM for PI3Kalpha, beta, and gamma isoforms, respectively, in a filter binding assay. It binds to both class I and class...
Keywords: | 1,3-dihydro-8-(6-methoxy-3-pyridinyl)-3-methyl-1-[4-(1-piperazinyl)-3-(trifluoromethyl)phenyl]-2H-imidazo[4,5-c]quinolin-2... |
Application: | Dual PI3K / FRAP inhibitor |
CAS | 1245537-68-1 |
MW: | 650.6 D |
From 54.00€
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Item number: SYN-1178-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. BGT226 is a novel, orally bioavailable small-molecule inhibitor of phosphoinositol-3-kinase and mammalian target of rapamycin with an IC(50) of 1nM. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
Keywords: | NVP-BEZ226, BEZ-226 |
Application: | PI3K / mTOR inhibitor |
CAS | 1245537-68-1 |
MW: | 650,6 D |
From 119.00€
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