3 products were found matching "1242156-23-5"!
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RN486
Item number: TGM-T1976-100mg
Description: RN486 is an effective and specific BTK inhibitor (IC50: 4 nM). Target: BTK. Smiles: CN1CCN(CC1)c1ccc(Nc2cc(cn(C)c2=O)-c2cccc(c2CO)-n2ccc3cc(cc(F)c3c2=O)C2CC2)nc1. References: Xu D, et al. J Pharmacol Exp Ther, 2012, 341(1), 90-103.
| Application: | BTK inhibitor |
| CAS | 1242156-23-5 |
| MW: | 606.69 D |
From 78.00€
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RN-486
Item number: Cay20536-1
RN-486 is a Bruton's tyrosine kinase inhibitor (Kd = 0.31 nM, IC50 = 4 nM) that displays a high degree of selectivity when tested against a panel of 369 kinases. It has been shown to block Fcepsilon receptor cross-linking-induced degranulation in mast cells (IC50 = 2.9 nM), Fcgamma receptor engagement-mediated...
| Keywords: | 6-cyclopropyl-2-[3-[1,6-dihydro-1-methyl-5-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-6-oxo-3-pyridinyl]-2-(hydroxyme... |
| Application: | BTK inhibitor |
| CAS | 1242156-23-5 |
| MW: | 606.7 D |
From 117.00€
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RN-486
Item number: LKT-R5212.1
Btk inhibitor.
| Keywords: | RN486 |
| Application: | Btk inhibitor |
| CAS | 1242156-23-5 |
| MW: | 606.69 D |
From 503.00€
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