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Item number: TGM-T14938-2mg

Description: CGP 36742 is a selective antagonist of the GABAB receptor that can penetrate the blood-brain barrier after peripheral administration (IC50: 32 µM). It is useful in the treatment of depression. Target: GABA Receptor. Smiles: P(CCCC)(CCCN)(=O)O. References: Nowak G, et al. Antidepressant-like activity of...

Keywords:	SGS-742
Application:	GABAB receptor antagonist
CAS	123690-78-8
MW:	179.2 D

83.00€ *

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CGP 36742

Item number: Cay35495-10

CGP 36742 is an antagonist of GABAB receptors (IC50 = 36 µM). It is selective for GABAB over a panel of 11 receptors, including GABAA, at 1 mM. CGP 36742 (3 mg/kg) reduces paired-pulse inhibition of the late inhibitory postsynaptic potential (IPSP) in CA1 pyramidal neurons in rats. It increases latency to step-down...

Keywords:	3-Aminopropyl-n-butylphosphinic Acid, SGS 742, P-(3-aminopropyl)-P-butyl-phosphinic acid
Application:	GABAB receptor antagonist
CAS	123690-78-8
MW:	179.2 D

From 204.00€ *

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