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Globalagliatin
Item number: TGM-T3104-10mg
Description: Globalagliatin (LY2608204) has been used in trials studying the treatment of Diabetes Mellitus, Type 2. Target: Glucokinase. Smiles: O=C(Nc1ncc(SCCN2CCCC2)s1)[C@@]1(C[C@H]1C1CCCCC1)c1ccc(cc1)S(=O)(=O)C1CC1. References: Gupta, M., & Vadde, R. (2019). Insights into the structure-function relationship of...
| Keywords: | LY2608204 |
| Application: | Glucokinase activator |
| CAS | 1234703-40-2 |
| MW: | 559.81 D |
From 33.00€
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LY2608204
Item number: Cay22914-1
LY2608204 is an activator of glucokinase (GK, EC50 = 42 nM). It stimulates glucose metabolism in INS-1E rat insulinoma cells (mean EC50 = 579 nM). LY2608204 (30 mg/kg) decreases plasma glucose levels in a dose-dependent manner in fasted rats.Formal Name:...
| Keywords: | (1R,2S)-2-cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]-cyclopropanecarbo... |
| Application: | Glucokinase activator |
| CAS | 1234703-40-2 |
| MW: | 559.8 D |
From 59.00€
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