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NIBR-0213
Item number: TGM-T28169-10mg
Description: NIBR-0213, a potent and selective S1P(1) antagonist, has efficacy in experimental autoimmune encephalomyelitis. Target: LPL Receptor. Smiles: CC=1C=C(C=C(C)C1C(N[C@H](C(O)=O)C)=O)C2=CC(N[C@H](C)C3=CC(C)=C(Cl)C=C3)=CC=C2. References: Bigaud M, Dincer Z, Bollbuck B, Dawson J, Beckmann N, Beerli C,...
| Keywords: | NIBR 0213 |
| Application: | S1PR1 antagonist |
| CAS | 1233332-14-3 |
| MW: | 464.98 D |
From 39.00€
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NIBR0213
Item number: Cay21513-5
NIBR0213 is an orally bioavailable, potent, and selective antagonist of sphingosine-1-phosphate receptor-1 (S1P1) with IC50 values of 2.5 and 2.0 nM for the hS1P1 in a Ca2+ mobilization assay and GTPgammaS assay, respectively. It is inactive at S1P2, S1P3, and S1P4 receptors (IC50s = >20, >10, and >10 µM,...
| Keywords: | N-[[3'-[[(1R)-1-(4-chloro-3-methylphenyl)ethyl]amino]-3,5-dimethyl[1,1'-biphenyl]-4-yl]carbonyl]-L-alanine |
| Application: | S1PR1 antagonist |
| CAS | 1233332-14-3 |
| MW: | 465 D |
From 48.00€
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