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Abemaciclib methanesulfonate
Item number: TGM-T3111-100mg
Description: Abemaciclib methanesulfonate (LY2835219) is a specific and effective inhibitor of CDK4(IC50=2 nM) and CDK6(IC50=10 nM). Target: CDK. Smiles: CS(O)(=O)=O.CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3cc(F)c4nc(C)n(C(C)C)c4c3)nc2)CC1. References: Sanchez-Martinez et al. Mol Cancer Ther, 2011,10(11 Suppl), Abstract nr...
| Keywords: | LY2835219, abemaciclib mesylate, LY2835219 mesylate, LY2835219 (methanesulfonate) |
| Application: | CDK4 / CDK6 inhibitor |
| CAS | 1231930-82-7 |
| MW: | 602.7 D |
From 31.00€
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LY2835219 (methanesulfonate)
Item number: Cay17740-1
LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 (CDK4) and CDK6 (IC50s = 2 and 10 nM, respectively). Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when...
| Keywords: | Abemaciclib,... |
| Application: | CDK4 / CDK6 inhibitor |
| CAS | 1231930-82-7 |
| MW: | 602.7 D |
From 60.00€
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LY2835219
Item number: CDX-L0303-M100
LY2835219 is an orally-bioavailable dual inhibitor of cyclin-dependent kinase 4 (CDK4) and CDK6 (IC50s = 2 and 10 nM, respectively). Through this mechanism, it blocks phosphorylation of retinoblastoma protein, resulting in arrest of cell cycling in the G1 phase. LY2835219 has antitumor action against xenografts when...
| Keywords: | LY2835219 methanesulfonate, Abemaciclib methanesulfonate, Abemaciclib mesylate, Bemaciclib |
| Application: | CDK4 / CDK6 dual inhibitor |
| CAS | 1231930-82-7 |
| MW: | 602.7 D |
From 230.00€
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Abemaciclib methanesulfonate
Item number: LKT-A044178.50
CDK inhibitor
| Keywords: | LY2835219 methanesulfonate,... |
| Application: | CDK inhibitor |
| CAS | 1231930-82-7 |
| MW: | 602.71 D |
From 188.00€
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