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Entospletinib
Entospletinib

Item number: TGM-T6101-100mg

Description: Entospletinib (GS-9973) (IC50= 7.7 nM)is a specific Syk inhibitor, which is orally bioavailable. Target: Syk. Smiles: C1CN(CCO1)c1ccc(Nc2nc(cn3ccnc23)-c2ccc3cn[nH]c3c2)cc1. References: J Med Chem. 2014, 57(9), 3856-3873.
Keywords: GS-9973
Application: Targets spleen tyrosine kinase [EC:2.7.10.2] (SYK)
CAS 1229208-44-9
MW: 411.46 D
From 33.00€ *
Review
GS-9973
GS-9973

Item number: Cay17653-1

Spleen tyrosine kinase (Syk) is a non-receptor tyrosine kinase that upon phosphorylation binds to immunoreceptor tyrosine-based activation motifs of FcRgamma chains and mediates downstream signaling related to platelet function and inflammation. GS-9973 is a potent Syk inhibitor (IC50 = 7.7 nM) that demonstrates...
Keywords: 6-(1H-indazol-6-yl)-N-[4-(4-morpholinyl)phenyl]-imidazo[1,2-a]pyrazin-8-amine
Application: Syk inhibitor
CAS 1229208-44-9
MW: 411.5 D
From 49.00€ *
Review
GS-9973
GS-9973

Item number: LKT-G7232.1

Syk inhibitor.
Keywords: GS9973, Entospletinib
Application: Syk inhibitor
CAS 1229208-44-9
MW: 411.46 D
From 156.00€ *
Review