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AM966
Item number: TGM-T4278-100mg
Description: AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release. Target: LPA Receptor, LPL Receptor. Smiles: C[C@@H](OC(=O)Nc1c(C)noc1-c1ccc(cc1)-c1ccc(CC(O)=O)cc1)c1ccccc1Cl. References: Swaney, JS, et al. A novel, orally active LPA1...
| Application: | LPAR1 antagonist |
| CAS | 1228690-19-4 |
| MW: | 490.93 D |
From 34.00€
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AM966
Item number: Cay22048-1
AM966 is an orally bioavailable, potent, and selective antagonist of the lysophosphatidic acid receptor 1 (LPA1) that has an IC50 value of 17 nM in a calcium assay using CHO cells transfected with the human LPA1 receptor. It is selective for LPA1 over the LPA2, LPA3, LPA4, and LPA5 receptors (IC50s = 1,700, 1,600,...
| Keywords: | 4'-[4-[[[(1R)-1-(2-chlorophenyl)ethoxy]carbonyl]amino]-3-methyl-5-isoxazolyl]-[1,1'-biphenyl]-4-acetic acid |
| Application: | LPAR1 antagonist |
| CAS | 1228690-19-4 |
| MW: | 490.9 D |
From 64.00€
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