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Item number: TGM-T6846-100mg

Description: Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7. Target: TLR, HBV, HCV Protease, HIV Protease, Apoptosis. Smiles: CCCCOc1nc(N)c2NC(=O)CN(Cc3cccc(CN4CCCC4)c3)c2n1. References: Rebbapragada I, et al. Molecular Determinants of GS-9620-Dependent TLR7...

Keywords:	GS-9620
Application:	Targets toll-like receptor 7 (TLR7)
CAS	1228585-88-3
MW:	410.51 D

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GS-9620

Item number: Cay19628-25

GS-9620 is an orally available agonist of toll-like receptor 7 (TLR7, EC50 = 291 nM) with 30-fold selectivity over TLR8 (EC50 = 9 µM). It has been shown to stimulate a TLR7 immune response in two different animal models of chronic hepatitis B infection and to inhibit HIV-1 infection in human peripheral blood...

Keywords:	Vesatolimod, 4-amino-2-butoxy-7,8-dihydro-8-[[3-(1-pyrrolidinylmethyl)phenyl]methyl]-6(5H)-pteridinone
Application:	TLR7 agonist
CAS	1228585-88-3
MW:	410.5 D

From 85.00€ *

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