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Item number: Cay25331-1

SCH 39166 is a dopamine D1 receptor antagonist (Ki = 5 nM). It is selective for D1 over D2-4 receptors (Kis = 3,751, >1,000, and 5,934 nM, respectively), however, it also binds to D5 receptors (Ki = 4.4 nM). SCH 39166 inhibits food intake in a dose-dependent manner in rats (ED50 = 0.84 mg/kg). It reduces ethanol...

Keywords:	11-chloro-7-methyl-6,6alphaS,7,8,9,13betaR-hexahydro-5H-benzo[d]naphtho[2,1-beta]azepin-12-ol, monohydrobromide
Application:	D1 receptor antagonist
CAS	1227675-51-5
MW:	394.7 D

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