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c-Kit-IN-1
c-Kit-IN-1

Item number: TGM-T4332-100mg

Description: c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM). Target: c-Kit, c-Met/HGFR. Smiles: Cn1cc(cn1)-c1cc(Oc2cc(F)c(NC(=O)C3(CC3)C(=O)Nc3ccccc3)cc2F)ccn1. References: Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative...
Keywords: PDGFR inhibitor 1, DCC-2618
Application: KIT / PDGFR inhibitor
CAS 1225278-16-9
MW: 489.47 D
From 38.00€ *
Review
c-Kit-IN-1
c-Kit-IN-1

Item number: Cay26174-1

c-Kit-IN-1 is a dual inhibitor of c-Kit and c-MET (IC50s = 50s = 50 = 98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.1 mg/ml, DMSO: 14 mg/ml, Ethanol: Partially soluble. lambdamax: 250 nm. SMILES:...
Keywords: N-[2,5-difluoro-4-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]phenyl]-N'-phenyl-1,1-cyclopropanedicarboxamide
Application: KIT / PDGFR inhibitor
CAS 1225278-16-9
MW: 489.5 D
From 43.00€ *
Review