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TPPU
Item number: Cay11120-1
Soluble epoxide hydrolase (sEH) converts epoxides to their corresponding diols. Inhibitors of sEH have anti-inflammatory, anti-hypertensive, neuroprotective, and cardioprotective effects. TPPU is a potent inhibitor of both human and mouse sEH (IC50 = 3.7 and 2.8 nM, respectively). The pharmacokinetics of this...
| Keywords: | N-[1-(1-oxopropyl)-4-piperidinyl]-N'-[4-(trifluoromethoxy)phenyl)-urea |
| Application: | sEH inhibitor |
| CAS | 1222780-33-7 |
| MW: | 359.3 D |
From 44.00€
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TPPU
Item number: TGM-T7199-100mg
Description: TPPU is a potent inhibitor of both human and mouse sEH (IC50 of 3.7 and 2.8 nM, respectively). Target: Epoxide Hydrolase. Smiles: CCC(=O)N1CCC(CC1)NC(=O)Nc1ccc(OC(F)(F)F)cc1. References: Pharmacokinetics and in vivo potency of soluble epoxide hydrolase inhibitors in cynomolgus monkeys[J]. British...
| Application: | sEH inhibitor |
| CAS | 1222780-33-7 |
| MW: | 359.34 D |
From 31.00€
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