2 products were found matching "1221713-92-3"!
No results were found for the filter!
NPS-1034
Item number: TGM-T6907-100mg
Description: NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively. Target: TAM Receptor, Apoptosis, c-Met/HGFR. Smiles: Cc1c(C(=O)Nc2ccc(Oc3ccnc4[nH]cc(-c5ccccc5)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)n1C. References: Rho JK, et al. Cancer Res. 2014, 74(1), 253-262.
| Keywords: | NPS 1034, NPS1034 |
| Application: | MET inhibitor |
| CAS | 1221713-92-3 |
| MW: | 551.54 D |
From 35.00€
*
NPS 1034
Item number: Cay19627-1
NPS 1034 is a dual inhibitor of the receptor tyrosine kinase activities of MET (IC50 = 48 nM) and AXL (IC50 = 10.3 nM), receptors for hepatocyte growth factor and vitamin K-dependent proteins, respectively. It synergistically inhibits cell proliferation when used in combination with gefitinib (Cay-13166) or...
| Keywords: | 2-(4-fluorophenyl)-N-[3-fluoro-4-[(3-phenyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-1H-py... |
| Application: | MET inhibitor |
| CAS | 1221713-92-3 |
| MW: | 551.6 D |
From 52.00€
*
