- Search results for 1220699-06-8
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3 products were found matching "1220699-06-8"!
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Item number: TGM-T7343-10mg
Description: PF-04979064 is a potent and selective PI3K and mTOR dual kinase inhibitor, with Ki values of 0.13 nM and 1.42 nM, respectively. Target: PI3K, mTOR. Smiles: C[C@H](O)C(=O)N1CCC(CC1)n1c2c(cnc3ccc(nc23)-c2ccc(C)nc2)n(C)c1=O. References: Cheng H , Li C , Bailey S , et al. Discovery of the Highly Potent...
Application: | PI3K / mTOR dual inhibitor |
CAS | 1220699-06-8 |
MW: | 446.5 D |
From 32.00€
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Item number: Cay39527-1
PF-04979064 is a dual inhibitor of PI3K and mTOR (Kis = 0.13, 0.111, 0.122, and 1.42 nM for PI3Kalpha, PI3Kgamma, PI3Kdelta, and mTOR, respectively). It is selective for PI3K and mTOR over a panel of 36 other kinases at 1 µM. PF-04979064 inhibits phosphorylation of Akt in BT-20 breast cancer cells (IC50 = 9.1 nM)....
Keywords: | 1,3-dihydro-1-[1-[(2S)-2-hydroxy-1-oxopropyl]-4-piperidinyl]-3-methyl-8-(6-methyl-3-pyridinyl)-2H-imidazo[4,5-c][1,5]napht... |
Application: | PI3K / mTOR dual inhibitor |
CAS | 1220699-06-8 |
MW: | 446.5 D |
From 35.00€
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Item number: SYN-1194-M001
Soluble in DMSO. PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50) of 9.1nM. Target: PI3K - mTOR , Kinase Group: Lipid Kinase , Substrate: Lipid
Keywords: | PF04979064 |
Application: | PI3K / mTOR inhibitor |
CAS | 1220699-06-8 |
MW: | 446,5 D |
From 256.00€
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