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CP-31398 dihydrochloride
CP-31398 dihydrochloride

Item number: TGM-T21648-100mg

Description: CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Target: p53. Smiles: Cl.Cl.COc1ccc(\C=C\c2nc(NCCCN(C)C)c3ccccc3n2)cc1. References: Rishu Takimoto, et al. The Mutant p53-Conformation...
Keywords: CP 31398 dihydrochloride
Application: p53 stabilizing agent
CAS 1217195-61-3
MW: 435.4 D
From 32.00€ *
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CP 31,398 (hydrochloride)
CP 31,398 (hydrochloride)

Item number: Cay27455-1

CP 31,398 is a p53 stabilizing agent. It increases active mutant p53 and p53 reporter gene expression without increasing total protein levels of p53 in H1299 lung cancer cells transfected with mutant p53. CP 31,398 is cytotoxic to a panel of 12 human glioma cell lines expressing wild-type or mutant p53 (EC50s =...
Keywords: N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine, dihydrochloride
Application: p53 stabilizing agent
CAS 1217195-61-3
MW: 435.4 D
From 46.00€ *
Review