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Item number: Cay21568-5

RGFP109 is a brain-penetrant inhibitor of histone deacetylases (HDACs, IC50s = 60 and 50 nM, Kis = 32 and 5 nM for HDAC1 and HDAC3 in cell-free assays, respectively). It has been shown to upregulate frataxin mRNA levels in cultured cells obtained from Friedreich's ataxia patients and in a GAA repeat-based mouse...

Keywords:	RG-2833, N-[6-[(2-aminophenyl)amino]-6-oxohexyl]-4-methyl-benzamide
Application:	Brain-penetrant HDAC inhibitor
CAS	1215493-56-3
MW:	339.4 D

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