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Item number: Cay28323-1

4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A (Cay-11352) that has anticancer activity. It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 µM) but not to carboplatin-resistant A2780 (A2780/CP70) cells (IC50 = >100 µM). It is selective for A2780 cells over non-cancerous...

Keywords:	(5beta,6beta,22R)-27-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,6-epoxy-22-hydroxy-1,4-dioxo-ergosta-2,24-dien-26-oic acid,...
Application:	Anticancer agent
CAS	1214886-31-3
MW:	582.9 D

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