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Alendronate sodium hydrate
Item number: TGM-T6373-50mg
Description: Alendronate sodium hydrate (MK 217) is a nitrogen-containing bisphosphonate, which is an effective inhibitor of bone resorption. It is utilized for the treatment and prevention of osteoporosis. Target: Transferase. Smiles: C(CC(O)(P(=O)(O)O)P(=O)(O)[O-])CN.O.[Na+].O.O. References: Fisher JE, et al. Proc...
| Keywords: | G-704650 Adronat, Fosamax, G-704650, Alendronate, MK 217, Alendronate sodium trihydrate |
| Application: | Targets farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] (FDPS) |
| CAS | 121268-17-5 |
| MW: | 325.12 D |
From 42.00€
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Alendronate (sodium hydrate)
Item number: Cay13642-100
Alendronate is an amino bisphosphonate that inhibits farnesyl pyrophosphate (FPP) synthase (IC50 = 50 nM for the recombinant human enzyme). It inhibits bone resorption in a pit formation assay using isolated rat osteoclasts (IC50 = 2 nM). Alendronate (3 and 10 µM) reduces angiotensin II-induced collagen I synthesis...
| Keywords: | Adronat, Fosamax, G-704650, MK-217, P,P'-(4-amino-1-hydroxybutylidene)bis-phosphonic acid, monosodium salt trihydrate (1:1:3) |
| Application: | Bone resorption inhibitor |
| CAS | 121268-17-5 |
| MW: | 325.1 D |
From 39.00€
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Alendronate Monosodium Trihydrate
Item number: LKT-A4515.100
A second generation bisphosphonate used as bone resorptive inhibitor.
| Application: | Bone resorptive inhibitor |
| CAS | 121268-17-5 |
| MW: | 325,08 D |
From 178.00€
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