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Item number: TGM-T36584-2mg

Description: HNMPA-(AM)3 inhibits activation of ERK phosphorylation and stimulation of ecdysteroid production by prothyrotropin (PTTH). Furthermore, HNMPA-(AM)3 had inhibitory effects on ecdysteroid production (IC50=14.2 µM) and insulin receptor activity (IC50=14.2 µM and 200 µM, in mosquitoes and mammals,...

Application:	Cell-permeable insulin receptor inhibitor prodrug
CAS	120944-03-8
MW:	454.36 D

200.00€ *

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HNMPA-(AM)3

Item number: Cay23245-1

HNMPA-(AM)3 is a cell-permeable prodrug form of the insulin receptor tyrosine kinase (IRTK) inhibitor HNMPA (Cay-15543). HNMPA-(AM)3 inhibits IRTK autophosphorylation in CHO cells expressing the human receptor in a concentration- and time-dependent manner. It inhibits 2-deoxyglucose uptake but does not affect...

Keywords:	P-[[(acetyloxy)methoxy]-2-naphthalenylmethyl]-phosphonic acid, bis[(acetyloxy)methyl] ester
Application:	Cell-permeable insulin receptor inhibitor prodrug
CAS	120944-03-8
MW:	454.4 D

From 67.00€ *

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