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Item number: TGM-T77697-100mg

Description: BML-278 is a SIRT1 activator with an EC150 of 1 µM. It increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, improving early embryonic development. BML-278 induces cell cycle arrest at the G1/S phase in primary human mesenchymal stromal cells, delaying...

Keywords:	BML278, BML 278
Application:	SIRT1 activator
CAS	120533-76-8
MW:	391.46 D

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BML-278

Item number: Cay20209-25

BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective concentration able to increase the enzyme by 150%) of 1 µM. It less potently activates SIRT2 and SIRT3 (EC150s = 25 and 50 µM, respectively). BML-278 induces hypoacetylation on alpha-tubulin in U937 cells that are pretreated with SAHA...

Keywords:	1,4-dihydro-4-phenyl-1-(phenylmethyl)-3,5-pyridinedicarboxylic acid, 3,5-diethyl ester
Application:	SIRT1 activator
CAS	120533-76-8
MW:	391.5 D

From 43.00€ *

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