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Item number: Cay38946-10

ThioLox is an inhibitor of 15-lipoxygenase 1 (15-LO-1, Ki = 3.3 µM). It also is an inhibitor of P. falciparum aspartate carbamoyltransferase (IC50 = 3.32 µM). ThioLox (50 µM) reduces LPS-induced expression of the mRNAs encoding TNF-alpha, inducible nitric oxide synthase (iNos), Il-1beta, Il-6, Il-8, and Il-12b in...

Keywords:	2-amino-N-butyl-5-phenyl-3-thiophenecarboxamide
Application:	15-LOX-1 (ALOX15) inhibitor
CAS	1202193-89-2
MW:	274.4 D

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