Description: BPKDi is a potent and selective inhibitor of PKD (protein kinase D). Target: Others. Smiles: C(N)(=O)C=1C=C(N=C(C1)N2CCNCC2)C=3C=C(NC4CCCCC4)N=CC3. References: Monovich L, Vega RB, Meredith E, Miranda K, Rao C, Capparelli M, Lemon DD, Phan D, Koch KA, Chapo JA, Hood DB, McKinsey TA. A novel kinase...

BPKDi is an inhibitor of protein kinase D (PKD, IC50s = 1, 9, and 1 nM for PKD1, PKD2, and PKD3, respectively). It is selective for PKD over PKCdelta and PKCepsilon, as well as over a panel of additional calcium/calmodulin-dependent protein kinase (CaMK) superfamily members, at 1 µM. It inhibits...