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Item number: TGM-T7041-100mg

Description: Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate dementia of the Alzheimer's type. Target: AChE. Smiles: O=C1C=2C(=CC(OC)=C(OC)C2)CC1CC3CCN(CC4=CC=CC=C4)CC3. References: Cacabelos R....

Keywords:	E2020, Donepezilo, Aricept
Application:	Targets acetylcholinesterase [EC:3.1.1.7] (ACHE)
CAS	120014-06-4
MW:	379.49 D

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Donepezil

Item number: Cay13245-10

Donepezil is an inhibitor of acetylcholinesterase (AChE, IC50 = 6.7 nM). It is selective for AChE over butyrylcholinesterase (BChE, IC50 = 988 nM). Donepezil (0.1 and 1 µM) inhibits the production of nitric oxide (NO) and TNF-alpha induced by oligomeric amyloid-beta (1-42) (AbetaO1-42) in primary rat microglial...

Keywords:	Aricept(R), 2,3-dihydro-5,6-dimethoxy-2[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one
Application:	AChE inhibitor
CAS	120014-06-4
MW:	379.5 D

From 44.00€ *

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