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Z944
Item number: TGM-T29201-100mg
Description: Z944 is a T-type calcium channel blocker. Z944 delays the progression of seizures in the amygdala kindling model. Z944 disrupts prepulse inhibition in both epileptic and non-epileptic rats. Target: Calcium Channel. Smiles: CC(C)(C)NC(=O)CN1CCC(CNC(=O)c2cc(F)cc(Cl)c2)CC1. References: Marks WN, Greba Q,...
| Keywords: | Z 944, Z-944 |
| Application: | Tremor treatment, Calcium channel blocker |
| CAS | 1199236-64-0 |
| MW: | 383.89 D |
From 48.00€
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Z944
Item number: Cay27679-5
Z944 is an inhibitor of T-type calcium channels (IC50s = 0.050-0.160 µM for the human recombinant voltage-gated calcium (Cav) channels Cav3.1, Cav3.2, and Cav3.3). It is selective for T-type channels over the N-type Cav2.2 channel (IC50 = 11 µM), as well as the rat L-type Cav1.2, human-ether-a-go-go (hERG/Kv11.1)...
| Keywords: | 4-[[(3-chloro-5-fluorobenzoyl)amino]methyl]-N-(1,1-dimethylethyl)-1-piperidineacetamide |
| Application: | T-type calcium channel inhibitor |
| CAS | 1199236-64-0 |
| MW: | 383.9 D |
From 44.00€
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