3 products were found matching "1197953-54-0"!
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Brigatinib
Item number: TGM-T3621-100mg
Description: Brigatinib (AP-26113) is a highly potent and selective inhibitor of ALK. Target: FLT, IGF-1R, EGFR, ROS, ALK. Smiles: COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1)N1CCC(CC1)N1CCN(C)CC1. References: Wei-Sheng Huang, et al. J Med Chem, 2016, 59(10):4948-4964.
| Keywords: | AP-26113 |
| Application: | Targets anaplastic lymphoma kinase [EC:2.7.10.1] (ALK, CD246) |
| CAS | 1197953-54-0 |
| MW: | 584.09 D |
From 31.00€
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AP26113
Item number: Cay19778-1
AP26113 is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK, IC50 12087), ceritinib (Cay-19374), and CH5424802 (Cay-18516). AP26113 blocks ALK activity and reduces growth in neuroblastoma cells, mouse xenograft, and Drosophila model systems harboring constitutively active ALK variants.Formal Name:...
| Keywords: | Brigatinib,... |
| Application: | Dual ALK / EGFR inhibitor |
| CAS | 1197953-54-0 |
| MW: | 584.1 D |
From 61.00€
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Brigatinib
Item number: CDX-B0374-M005
White to yellow solid. Soluble in DMSO. Sligthly soluble in ethanol. Insoluble in water. Chemical. CAS: 1197953-54-0. Formula: C29H39ClN7O2P. MW: 584.09. Synthetic. Brigitanib acts as a tyrosine kinase inhibitor with activity against multiple kinases including ALK, ROS1, insulin-like growth factor 1 receptor and...
| Keywords: | AP26113,... |
| CAS | 1197953-54-0 |
| MW: | 584,09 D |
From 91.00€
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