- Search results for 119413-54-6
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3 products were found matching "119413-54-6"!
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Item number: TGM-T1174-100mg
Description: Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer. Target: Autophagy, Apoptosis, Topoisomerase. Smiles: Cl.CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(O)c(CN(C)C)c4cc3Cn1c2=O. References: Caceres G, et al. Anticancer Drugs. 2003, 14(7), 569-574.
Keywords: | NSC 609669, Nogitecan HCl, SKF 104864A, SKFS 104864A, NSC609699, Topotecan HCl |
Application: | Targets DNA topoisomerase I [EC:5.6.2.1] (TOP1) |
CAS | 119413-54-6 |
MW: | 457.92 D |
From 31.00€
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Item number: Cay14129-5
Topotecan is an inhibitor of DNA topoisomerase I and a derivative of the DNA topoisomerase I inhibitor camptothecin (Cay-11694). Topotecan inhibits DNA topoisomerase I in human MCF-7 breast and DU-145 prostate cancer cells with IC50 values of 13 and 2 nM, respectively, in a cell-based luciferase reporter assay....
Keywords: | NSC 609669, SKF 104864A,... |
Application: | Topoisomerase I inhibitor |
CAS | 119413-54-6 |
MW: | 457.9 D |
From 43.00€
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Item number: LKT-T5761.5
A topoisomerase I inhibitor that is a water soluble semisynthetic camptothecin. Hygroscopic!
Application: | Topoisomerase I inhibitor |
CAS | 119413-54-6 |
MW: | 457,9 D |
From 81.00€
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