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Item number: TGM-T2S0300-10g

Description: Dihydrocoumarin (melilotin) is a compound found in Melilotus officinalis. Dihydrocoumarin is a yeast Sir2p inhibitor. Dihydrocoumarin also inhibits human SIRT1 and SIRT2 with IC50s of 208 µM and 295 µM, respectively. Target: Sirtuin. Smiles: O=C1CCC2=C(O1)C=CC=C2. References: Podyma W, Baczek K,...

Keywords:	Chroman-2-one, melilotin, Hydrocoumarin, 2-chromanone, 3,4-dihydrocoumarin
CAS	119-84-6
MW:	148.16 D

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Dihydrocoumarin

Item number: Cay33495-10

Dihydrocoumarin is a coumarin that has been found in M. officinalis and has enzyme inhibitory activity. It inhibits the activities of sirtuin 1 (SIRT1) and SIRT2 (IC50s = 208 and 295 µM, respectively, for the human enzymes). Unlike coumarin, dietary administration of dihydrocoumarin (0.76%) does not induce...

Keywords:	DHC, 3,4-dihydro-2H-1-benzopyran-2-one
Application:	Coumarin, SIRT1/2 inhibitor, Flavoring agent
CAS	119-84-6
MW:	148.2 D

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