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Item number: Cay29414-1

Mitoxantrone-d8 is intended for use as an internal standard for the quantification of mitoxantrone (Cay-14842) by GC- or LC-MS. Mitoxantrone is an inhibitor of DNA topoisomerase IIalpha and HIV-1 integrase (IC50s = 5.3 and 3.8 µM, respectively). It intercalates into DNA in a cell-free assay when used at a...

Keywords:	1,4-dihydroxy-5,8-bis[[2-[(2-hydroxyethyl-1,1,2,2-d4)amino]ethyl]amino]-9,10-anthracenedione
Application:	GC-MS, LC-MS, Internal standard, Topoisomerase II inhibitor, HIV-1 integrase inhibitor
CAS	1189974-82-0
MW:	452.5 D

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