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Item number: TGM-TQ0084-100mg

Description: lumateperone Tosylate (ITI-007) is a 5-HT2A receptor antagonist (Ki: 0.54 nM), a SERT blocker (Ki: 61 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki: 32 nM). Target: Dopamine Receptor, 5-HT Receptor. Smiles:...

Keywords:	ITI-007
Application:	Targets 5-hydroxytryptamine receptor 2 (HTR2)
CAS	1187020-80-9
MW:	565.7 D

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Lumateperone (tosylate)

Item number: Cay34541-10

Lumateperone is an atypical antipsychotic. It selectively binds to the serotonin (5-HT) receptor subtype 5-HT2A over 5-HT1A and 5-HT2C receptors (Kis = 0.54, 1,480, and 173 nM, respectively). Lumateperone also binds to dopamine D1, D2, and D4 receptors (Kis = 52, 32, and 108 nM, respectively), alpha1A- and...

Keywords:	ITI-007,...
Application:	Atypical antipsychotic
CAS	1187020-80-9
MW:	565.7 D

From 78.00€ *

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