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DBPR108
Item number: Cay41117-10
DBPR108 is an inhibitor of dipeptidyl peptidase 4 (DPP-4, IC50 = 0.015 µM). It is selective for DPP-4 over DPP-8 and DPP-9 (IC50s = >50 µM for both). DBPR108 (10 mg/kg) increases plasma levels of glucagon-like peptide 1 (GLP-1) and insulin in rats. It reduces blood glucose levels in an oral glucose tolerance test in...
| Keywords: | Prusogliptin, 1-[2S-[[1,1-dimethyl-3-oxo-3-(1-pyrrolidinyl)propyl]amino]acetyl]-4S-fluoro-2-pyrrolidinecarbonitrile |
| Application: | DPP-4 inhibitor |
| CAS | 1186426-66-3 |
| MW: | 324.4 D |
From 136.00€
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DBPR108
Item number: TGM-T15079-100mg
Description: DBPR108 is an orally bioavailable dipeptide-derived DPP4 inhibitor (IC50: 15 nM) and it has no inhibition on DDP8 and DPP9. Target: DPP-4, Proteasome. Smiles: CC(C)(CC(=O)N1CCCC1)NCC(=O)N1C[C@@H](F)C[C@H]1C#N. References: Yeh TK, et al....
| CAS | 1186426-66-3 |
| MW: | 324.39 D |
From 70.00€
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