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NVP-BVU972
Item number: TGM-T2680-100mg
Description: NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM. Target: c-Met/HGFR. Smiles: Cn1cc(cn1)-c1ccc2ncc(Cc3ccc4ncccc4c3)n2n1. References: Tiedt R, et al. Cancer Res. 2011, 71(15), 5255-5264.
| Application: | Met kinase inhibitor |
| CAS | 1185763-69-2 |
| MW: | 340.38 D |
From 42.00€
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NVP-BVU972
Item number: Cay34495-1
NVP-BVU972 is an inhibitor of Met kinase (IC50 = 14 nM). It is selective for Met over a panel of 62 additional kinases (IC50s = >1 µM for all). It inhibits proliferation of Met-amplified GTL-16 gastric, MKN45 gastric, and EBC-1 lung cancer cells (IC50s = 66, 32, and 82 nM, respectively). NVP-BVU972 inhibits Met...
| Keywords: | 6-[[6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]methyl]-quinoline |
| Application: | Met kinase inhibitor |
| CAS | 1185763-69-2 |
| MW: | 340.4 D |
From 78.00€
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