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TG6-129
Item number: TGM-T28958-100mg
Description: TG6-129 is an antagonist of the EP2 receptor. TG6-129 suppresses PGE2-induced elevation of cAMP in cells expressing EP2 with an IC50 value of 1.6 µM. TG6-129 reduces the expression of COX-2, IL-1beta, IL-6, IL-12, IL-23 and TNF-alpha induced by the EP2-selective agonist butaprost in P388D1 macrophages....
| Keywords: | TG6 129 |
| Application: | EP2 receptor antagonist |
| CAS | 1164464-14-5 |
| MW: | 491.58 D |
From 122.00€
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TG6-129
Item number: Cay19085-1
Prostaglandin E2 (PGE2, Cay-14010) evokes distinct responses through four different 'E prostanoid' (EP) receptors. EP2 is a G protein-coupled receptor that has diverse roles, including those in cancer, inflammation, and neuroprotection. TG6-129 is an antagonist of the EP2 receptor, suppressing PGE2-induced elevation...
| Keywords: | SID 17503974,... |
| Application: | EP2 receptor antagonist |
| CAS | 1164464-14-5 |
| MW: | 491.6 D |
From 61.00€
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